RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-29b
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Masson's trichrome staining; PCR; etc.
Target
SMAD3
Pathway
NA
PubMed ID
Title
MicroRNA-29b mediates the anti-fibrotic effect of tanshinone IIA in post-infarct cardiac remodeling
Year
2014
Function
"Tanshinone IIA (TSN) exerts antifibrotic effects in postinfarct cardiac fibrosis by upregulating the expression of miR-29b, which is mediated by the TGF-beta-smad3 signaling pathway."